Dre Greenlaw practiced for the first time this week since he tore his Achilles in the Super Bowl. Here's what head coach Kyle ...

The San Francisco 49ers have had issues with penalties this year, and now general manager John Lynch is speaking on the issue ...

The San Francisco 49ers promoted CB Nick McCloud to the active roster from the team's practice squad and activated LB Jalen ...

The National Weather Service has extended its "lake effect snow warning" in Buffalo through Monday at 7 p.m. ET, with ...

On Saturday, the San Francisco 49ers announced the following roster moves ahead of Sunday's snowy game in Buffalo against the ...

Yet on Sunday night in frigid Orchard Park, the 49ers, mired at 5-6 and a game out of first place in the NFC West, find their ...

The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

The Buffalo Bills have activated Matt Milano from injured reserve, putting the starting linebacker in position to play Sunday ...

The San Francisco 49ers (5-6) try to salvage their season against the Buffalo Bills (9-2) on Sunday Night Football. Kickoff ...

Running back Christian McCaffrey says the San Francisco 49ers are “hungry” to make a playoff push even with the defending NFC ...

as the Bills host the San Francisco 49ers. This is the fifth time the Bills are playing in prime-time this year and they are ...

Watch out for the tables on "Sunday Night Football." The nightcap of Sunday's action will be in northern New York with the ...