Urging Iranians to overthrow their clerical rulers, the US launched "major combat operations" along with Israel against Iran early on Saturday. The US is calling the operation "Epic Fury", while the Israelis call it "Lion's Roar".

American military assets in the region and Gulf oil supplies are vulnerable to attack and Israel is a renewed target

World leaders have been responding cautiously amid U.S. and Israeli strikes on Iran, reports of its supreme leader's death and fears of a wider war.

Confirmation follows statement by US president that Khamenei’s death is ‘justice for the people of Iran’ amid call for regime change

A massive U.S.-Israeli joint military offensive called “Operation Epic Fury” is underway in Iran, targeting Islamic Republic regime leadership and military targets that pose an "imminent threat."

Paul Salem of the Middle East Institute noted that Trump’s message has shifted sharply. While just days ago he framed potential U.S. strikes as leverage to push Iran toward a nuclear deal, his speech announcing them openly called for regime change.

The national mood is somewhere between anxiety, resignation and anticipation as President Trump considers whether to attack Iran.