Late in the fourth quarter, first-round pick defensive end Mykel Williams went down with a right knee injury. Afterwards, coach Kyle Shanahan told reporters that they fear Williams injured his ACL. A torn ACL would sideline Williams for the remainder of the season.

NFL.com says teams are calling on Jauan Jennings, but with Aiyuk still ramping up and Shanahan signaling stability, a 49ers trade is unlikely.

The San Francisco 49ers will have to wait at least another week before their starting quarterback is in uniform.

So what’s it going to be this week with the New York Giants, who host the San Francisco 49ers? Will we see the team that held its own against the Los Angeles Ch

Mac Jones delivered another strong performance for the 49ers, but his final move of the game showed his true character.

The New York Giants play host to the San Francisco 49ers on Sunday in a battle of teams missing multiple star players on both sides of the ball.

Mac Jones, Christian McCaffrey and the Niners made winning look easy against the Giants. It won’t always work that way.

In Sunday’s 34-24 win over the New York Giants, Niners first-round pick Mykel Williams left the game with a knee injury the team fears could be a significant ACL injury, according to head coach Kyle Shanahan. Shanahan told reporters the team won’t know for sure until after an MRI on Monday.