Medically reviewed by Jeffrey S. Lander, MD ATTR-CM is an acronym for the medical condition called transthyretin amyloid cardiomyopathy. There are two causes of ATTR-CM, an inherited gene mutation and ...

Hereditary transthyretin amyloidosis (hATTR) with polyneuropathy is a rare disorder passed down in families that gets worse over time. It’s a result of a change in a gene, also called a mutation.

Among members of the Richardson family who carry a mutation in the PSEN1 gene, the average age when symptoms start is 39.

Reiswig, like many members of his family, carries a mutation in a gene called presenilin-2, which causes his brain to overproduce amyloid plaques.

Voyager Therapeutics presents data on tau silencing therapy VY1706 and anti-amyloid therapy at ASGCT 2025.

Wainua is an injectable medicine. Here’s how it treats hereditary transthyretin-mediated amyloidosis (hATTR).

Scientists are just beginning to understand the microbes that have been with us for millennia — the so-called microbiome, ...

- Featured data also include anti-amyloid gene therapy for Alzheimer’s disease, as well as multiple presentations on Voyager’s continued enhancements to its highly BBB penetrant novel capsids - ...

The Christchurch mutation, which protects against tau pathology and cognitive deterioration despite extensive amyloid buildup, offers an important clue. This rare mutation is found in the APOE gene ...

Researchers at the Federal University of São Carlos (UFSCar) in the state of São Paulo, Brazil, are developing a panel of ...

A new dosing regimen for Kisunla, to help lower the risk of certain side effects, has been approved by the U.S. Food and Drug ...

- Featured data also include anti-amyloid gene therapy for Alzheimer’s disease, as well as multiple presentations on Voyager’s continued enhancements to its highly BBB penetrant novel capsids - ...