A micrograph showing inflammatory responses in the cortex of the new model mouse. Alzheimer's disease patients and mouse ...

called amyloid precursor protein, into smaller pieces, one of which is amyloid beta. Previous work by the research team had ...

Goldstein and his colleagues studied the role of amyloid precursor protein (APP), which gives rise to the abnormal ... To complement the mouse studies, the researchers studied the effects of various ...

And though drugs that have some effect on Alzheimer’s disease, dementia’s most common manifestation, have recently been assessed in America and Britain, not everyone is convinced. The European Union’s ...

Dismissal of long-standing Alzheimer's research ignores the voices of those who matter most: patients, caregivers and doctors.

Researchers have dosed the first participant in a clinical trial of an investigational medicine designed to lower the amount ...

A single injection of Alnylam’s RNA interference candidate ALN-APP – which is designed to switch off the production of amyloid precursor protein ... shown to achieve gene silencing in the ...

Genetics researchers studied eFAD families to discover the three known genes that cause familial AD: amyloid precursor protein (APP), presenilin-1 (PS1 ... Tests can determine which gene is at fauly ...

Dementia affects millions of people worldwide, causing a serious impact on the economy and the healthcare system. Alzheimer’s ...

The paper T. Liu et al., “The amyloid precursor protein is a conserved Wnt receptor,” eLife, 10:e69199, 2021. Amyloid precursor protein, which generates amyloid-β when broken down, has long been ...