We examined acetylcholinesterase, plasma neuronal proteins, secreted beta-amyloid precursor protein (APP), and amyloid-beta 40 and amyloid-beta 42 peptides in children with and without autism.

Researchers have developed a tau-targeting vaccine that could help prevent the progression of Alzheimer’s disease by ...

While much research has focused on this amyloid beta protein ... They attached fluorescent tags to antibodies that would bind ...

Aβ is produced from the sequential proteolysis of amyloid precursor protein ... the amyloid-forming protein being targeted, the stage of disease progression and the antibody being used.

A single injection of Alnylam’s RNA interference candidate ALN-APP – which is designed to switch off the production of amyloid precursor protein ... generation of antibody-based amyloid ...

University of New Mexico Health Sciences researchers hope to launch human clinical trials in their quest for a vaccine to prevent the buildup of ...

"The inherited form of Alzheimer's disease can be caused by mutations to the gene that encodes for the amyloid precursor protein," explains ... of the amyloid beta peptides into fibrillar ...

The paper T. Liu et al., “The amyloid precursor protein is a conserved Wnt receptor,” eLife, 10:e69199, 2021. Amyloid precursor protein, which generates amyloid-β when broken down, has long been ...

Márcia’s research also focuses on ADAM-10, a metalloprotease that regulates amyloid precursor protein processing and beta-amyloid plaque ... such as monoclonal antibodies, if needed,” Márcia ...

At most, we observed a slight astrocyte response using immunostaining with antibody against glia fibrillary acidic protein (data not shown). These data indicate that clearance of amyloid-β after ...