While much research has focused on this amyloid beta protein ... They attached fluorescent tags to antibodies that would bind ...

Researchers have developed a tau-targeting vaccine that could help prevent the progression of Alzheimer’s disease by ...

A single injection of Alnylam’s RNA interference candidate ALN-APP – which is designed to switch off the production of amyloid precursor protein ... generation of antibody-based amyloid ...

Researchers hope to launch human clinical trials in their quest for a vaccine to prevent the buildup of pathological tau after demonstrating that this vaccine generated a robust immune response in ...

Background: The amyloid precursor protein (APP) is genetically associated with Alzheimer's disease (AD). Elucidating the function of APP should help understand AD pathogenesis and provide insights ...

Alzheimer's disease may be the most common dementia, but amyloid-beta (Aβ) plaques and tau ... an extra copy of the gene for amyloid precursor protein and thus higher production of Aβ peptides ...

The paper T. Liu et al., “The amyloid precursor protein is a conserved Wnt receptor,” eLife, 10:e69199, 2021. Amyloid precursor protein, which generates amyloid-β when broken down, has long been ...

Science X is a network of high quality websites with most complete and comprehensive daily coverage of the full sweep of science, technology, and medicine news ...

At most, we observed a slight astrocyte response using immunostaining with antibody against glia fibrillary acidic protein (data not shown). These data indicate that clearance of amyloid-β after ...

Márcia’s research also focuses on ADAM-10, a metalloprotease that regulates amyloid precursor protein processing and beta-amyloid plaque ... such as monoclonal antibodies, if needed,” Márcia ...

University of New Mexico Health Sciences researchers hope to launch human clinical trials in their quest for a vaccine to ...