These infections—systemic, lethal infestations of the body’s deep tissues and organs—have little in common with the ...

auris is often resistant to disinfectants and antifungal drugs ... do not always apply: when drug resistance emerges in fungi, it often does so through molecular mechanisms different from those ...

The discovery of a new preclinical compound with strong antifungal activity against multidrug-resistant pathogens is ...

Writing in Nature, researchers from China Pharmaceutical University and Shandong University have revealed the discovery of a new polyene antifungal antibiotic, mandimycin.

An often-overlooked mechanism of gene regulation may be involved in the failure of antifungal drugs in the clinic ... used the known mode of action of fluorocytosine on A. fumigatus as the ...

"For decades, clinicians have relied on a handful of antifungal classes, with few mechanisms of action and significant limitations due to spectrum of activity, drug toxicities, or drug-drug ...

Since mid-2002, two new antifungal drugs — voriconazole ... Both drugs have greater efficacy (because of their specific mechanisms of action), more favourable toxicity profiles and are much ...

GSK said this mechanism of action is intended to provide activity ... In 2023, GSK licensed rights to the Syncexis antifungal drug Brexafemme, which is approved for treating vaginal yeast infections.

Basilea Pharmaceutica Ltd, Allschwil (SIX: BSLN), a commercial-stage biopharmaceutical company committed to meeting the needs of patients with severe bacterial and fungal infections, announced today ...