A collaborative effort is trying to construct the cell atlas of the developing brains of humans and animal models. Using advanced single-cell and spatial technologies, they mapped how brain cell types ...
This illustration summarizes how integrated spatial transcriptomics, single-cell transcriptomics, single-cell epigenomics, and spatial epigenomics enable multi-dimensional profiling of the tumor ...
At the turn of the 20th century, Korbinian Brodmann released one of the most consequential brain maps ever. By studying the humps, grooves, layers, and cells of the cortex—the outermost layer of the ...
Disrupting maternal gut-immune axis perturbed immune networks in developing mouse brains, revealing potential mechanisms underlying neurodevelopmental disorders.
Like the seeds of a forest, a few cells in embryos eventually sprout into an ecosystem of brain cells. Neurons get the most recognition for their computing power. But a host of other cells provides ...
When a neuron in our body gets damaged, segments of RNA produce proteins that can help repair the injury. But in neurological disorders such as ALS and spinal muscular atrophy, or following spinal ...
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Understanding the impact of pregnancy stressors on neuroimmune landscape of the fetal brain
The maternal microbiome and immune system have both independent and synergistic effects on fetal brain health - changes in ...
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