Scientists have unearthed 188 previously unknown types of CRISPR systems buried in the genomes of simple microorganisms. Best known as a powerful gene-editing tool, CRISPR actually comes from an ...

Results from the CRISPR-Cas Type IV-A3-mediated antibiotic-resistance re-sensitization assay conducted by the researchers. Credit: Fabienne Benz CRISPR-Cas systems have revolutionized biotechnology by ...

The discovery of CRISPR-Cas gene editing technology has revolutionized biological research, providing new insights and opportunities for the advancement of several industries. However, the ...

Employing a metagenomic search, we identified a family of miniature CRISPR-Cas type V-L systems capable of RNA-guided dsDNA target cleavage without a tracrRNA. A bacterial depletion screen revealed ...

The cryogenic electron microscope structure of the A4p-activated (green) CalpL protein filament (violet) from Candidatus Cloacimonas acidaminovorans (PDB ID: 9EYJ). CRISPR-Cas systems help to protect ...

With the first medical therapy approved and systems like CRISPR-Cas showing up in complex cells, there’s a lot happening in the genome editing field. By Amber Dance/Knowable Magazine Published Jan 26, ...

Like humans, bacteria and archaea can be attacked by viruses. These microorganisms have developed their own immune defense strategies against their pathogens. Bacterial defenses, such as CRISPR-Cas ...

CRISPR-Cas 9 is a gene-editing tool that made it possible to rewrite any organism's genetic code and tackle genetic diseases more effectively. Known as genetic scissors, CRISPR identifies a DNA ...

CRISPR has revolutionized science. AI is now taking the gene editor to the next level. Despite its real-world impact, CRISPR isn’t perfect. The tool snips both strands of DNA, which can cause ...

CRISPR-Cas systems are bacterial adaptive immune systems that target and cut the nucleic acids (DNA/RNA) of invading genetic parasites like bacteriophages (phages); viruses that infect - and ...