which in turn launches a series of biochemical reactions within the cell. These intracellular signaling pathways, also called signal transduction cascades, typically amplify the message ...

Cellular signaling is an elaborate, dynamic, and interactive system of inter- and intracellular communication, responsible for governing and coordinating activities, from the basic to the complex.

How do these molecules activate signaling pathways in their target cells? They bind to cell-surface proteins of the seven-helix-G protein-coupled receptors (GPCRs). These in turn activate either ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...