Expert Rev Endocrinol Metab. 2013;8(2):183-193. Mitotane reduces cortisol synthesis through the inhibition of 11B-hydroxylase, 18-hydroxylase, 3-α hydroxylase, hydroxysteroid dehydrogenase and several ...

Internet trolls partly aided doctors in diagnosing Amy Schumer with Cushing syndrome, but patients can go years without a diagnosis. Schumer opened up about her February 2024 diagnosis on the “Call ...

Cushing's syndrome, defined by chronic cortisol excess, is well established as a disorder with multisystem implications. One of its critical complications is a hypercoagulable state that significantly ...

Comedian Amy Schumer revealed internet criticism led her to seek medical advice and a subsequent diagnosis of Cushing syndrome. Schumer shares her relief upon learning it was a treatable condition and ...

The FDA warned Corcept Therapeutics that it would face significant hurdles if it submitted its lead rare disease asset for approval, contradicting the biotech’s claims that the candidate’s eventual ...

Agents that directly lower ACTH secretion by a pituitary adenoma represent an attractive option for the treatment of Cushing's disease, as these drugs directly target the pathogenesis of disease.