Scientists have tapped into the Summit supercomputer to study an elaborate molecular pathway called nucleotide excision ...

Sunburns and aging skin are obvious effects of exposure to harmful UV rays, tobacco smoke and other carcinogens. But the effects aren't just skin deep. Inside the body, DNA is literally being torn ...

Replication checkpoints have key roles in promoting replication fork stability. Different types of DNA lesions elicit the action of diverse damage-tolerance pathways that restore replication fork ...

Scientists have uncovered a hidden driver of ovarian cancer—high-risk mesenchymal stem cells lurking in the fallopian tubes.

Neurons collected from brain lesions in MS patients were found to accumulate new genetic mutations faster than healthy nerve ...

Ultraviolet (UV) radiation from the sun is a well-known cause of DNA damage, which can lead to diseases like skin cancer. But how do our cells repair this damage to protect us? Researchers from ...

Thymine dimers are a common type of UV-induced DNA lesion and are associated with skin cancer risk. During DNA replication, the complementary base pairing of thymine with adenine ensures the accurate ...

Researchers at Georgia State University used the Summit supercomputer to study an elaborate molecular pathway called ...