The morphinelike compound McDougall refers to is known as endomorphin 1, and his team studied whether peripheral administration of this endogenous ¿-opioid peptide could reduce knee joint pain.

Endogenous opioid peptides are the neurochemical basis of the anesthetic and analgesic effects of acupuncture. The quantity of acupuncture stimulus can be controlled accurately by using ...

A clinical trial of an experimental drug for treatment-resistant major depression finds that modulation of the endogenous opioid system may improve the effectiveness of drugs that target the action of ...

New research undertaken by American and Chinese researchers may pave the way for safer opioid painkillers, thanks to the use of cryo-electron microscopy (cryo-EM) to examine the detailed structures of ...

Everyone knows that stubbing your toe hurts. What makes it stop hurting is the body's main pain-blocking process - the natural production of opioids. Cognitive-based approaches found to reduce pain, ...

Given how profound an influence opioids have on the world – for better or worse – scientists know surprisingly little about how these drugs actually work. A recent study led by researchers from ...

In a new study evaluating meditation for chronic lower back pain, researchers at University of California San Diego School of Medicine have discovered that men and women utilize different biological ...