The epithelial–mesenchymal transition is the process by which polarised epithelial cells that are connected via adhesion lose their characteristics and acquire migratory and invasive properties ...

Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype known as triple-negative breast cancer (TNBC).

The following is a summary of “Cytokeratin 17 activates AKT signaling to induce epithelial-mesenchymal transition and promote bladder cancer progression,” published in the April 2025 issue of BMC ...

The developmental program Epithelial-Mesenchymal Transition (EMT) is frequently re-activated in metastatic and recurrent tumors. Our work provided a conceptual understanding depicting a causal role ...

Background Muscle wasting and weakness (sarcopenia) are commonly associated with COPD causing frailty and reduced quality of ...

Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial unfolded protein ...

Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype ...

These processes are called the epithelial-to-mesenchymal transition (EMT) and the reverse mesenchymal-epithelial-transition (MET), and they enable cells to reversibly switch between stationary and ...

ENO2 overexpression promoted the migration and invasion of HNSCC cells both in vitro and in vivo, and this effect was mediated by the epithelial-mesenchymal (EMT) transition. Further studies ...