such as when cells interact with the surrounding extracellular matrix or with their immediate neighbors. This type of signaling is especially important to the structure and function of tissues.

The work is published in the journal Nature Methods. The extracellular matrix supports and gives structure to our cells and tissues: It provides a scaffold for cells to grow in, dictates the ...

Like most tissues, the skin consists of cells that are embedded in a so-called extracellular matrix: a network of proteins ...

Within multicellular organisms, tissues are organized communities of cells that work together to carry out a specific function. The exact role of a tissue in an organism depends on what types of ...

Growing cells in the laboratory is an art that humans have mastered decades ago. Recreating entire three-dimensional tissues is much more challenging. Researchers are developing a new hydrogel-based ...

Our group has explored the regeneration of soft biological tissues through cell-extracellular matrix interactions, with a focus on collagen-rich environments and fibrosis. We have developed a new ...

It is now clear that an individual cell can change how it moves in response to the material surrounding it. Petrie's lab is interested in understanding how the structure of the three-dimensional (3D) ...

Researchers in Nikolaus Rajewsky's lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor's cellular neighborhoods in 3D and identify potential targets ...