From the earliest studies with epithelial cells implanted into detrusor muscle to later experiments on smooth muscle in defined collagen gels, cell niche and extracellular matrix (ECM) have been ...

Growing cells in the laboratory is an art that humans have mastered decades ago. Recreating entire three-dimensional tissues is much more challenging. Researchers are developing a new hydrogel-based ...

Biotechnology pioneer Halozyme has developed ENHANZE, a drug delivery technology that can enable and optimize the subcutaneous ... in the extracellular matrix of the SC space, which enables ...

The enzyme temporarily hydrolyses hyaluronan in the extracellular matrix of the subcutaneous layer of skin, making it possible to deliver larger volumes of drug material and improve dispersion and ...

Like most tissues, the skin consists of cells that are embedded in a so-called extracellular matrix: a network of proteins and other biomolecules that provides the tissue with shape and structure and ...