Cells in the developing heart must find the perfect match, much like a game of microscopic speed dating. Using filopodia—tiny ...

Filopodia are specialized structures that extend from the cell membrane to allow a cell to explore the environment around it. These thin protrusions are full of a protein called actin, which, in ...

Computer simulations of filopodia dynamics indicate that a rotating actin structure inside the tube results in friction between the membrane and the actin, leading to the spiral form that is observed.

The study titled "Ceramide-mediated orchestration of oxidative stress response through filopodia-derived small extracellular vesicles" was recently published in the Journal of Extracellular Vesicles.

Tip cell filopodia express high-affinity tyrosine kinase receptors for VEGF, which dimerize and autophosphorylate upon ligand binding. VEGF receptor activation promotes its internalization and the ...