Arrows indicate the sites targeted for the effect of immune globulin. Immune globulin interferes with the selection of B-cell repertoires, down-regulates or up-regulates antibody production ...

Efficacy of low dose antithymocyte globulin on overall survival, relapse rate, and infectious complications following allogeneic peripheral blood stem cell transplantation for leukemia in children ...

Anti-thymocyte globulin (ATG) is polyclonal, containing Ab specificities capable of binding to various immune-cell subsets implicated in the pathogenesis of GVHD, including T cells, B cells ...

Giving patients undergoing blood stem cell transplantation from an unrelated donor, standard graft-versus-host-disease (GVHD) prophylaxis in combination with anti-T-cell globulin (ATG), prevents ...

One-year data suggest allogeneic stem cell-derived islet-cell therapy could become a future option for those with type 1 ...

Walker I, Panzarella T, Couban S, et al: Pretreatment with anti-thymocyte globulin versus no anti-thymocyte globulin in patients with haematological malignancies undergoing haemopoietic cell ...

An albumin/globulin (A/G) ratio test measures the two main proteins in your blood. Low or high results can indicate certain health conditions.

Globulin. This is a group of proteins. ... Low A/G ratio: This might be the sign an autoimmune disorder, where your body’s immune system attacks healthy cells.

IVIg, which stands for intravenous immune globulin, refers to highly purified antibodies that are isolated from donated blood and administered in a large dose through the vein, or “intravenous.” There ...

It develops when blood cells formed from the donor's stem cells think your cells are foreign and attack them. Between 30% and 70% of patients with a donor stem cell transplant get some form of GvHD.

Recently, intravenous immune globulin, which contains naturally occurring antibodies, was shown to contain antibodies to Aβ peptides, and in both in vitro neuronal-cell cultures and an in vivo ...

Antithymocyte Globulin for Graft-Versus-Host Disease Prophylaxis After Allogeneic Hematopoietic Stem-Cell Transplantation. JCO 35 , 3993-3995 (2017). DOI: 10.1200/JCO.2017.76.0512 ...