A recent study from the Institute of Biomedicine at the University of Eastern Finland shows that the glucocorticoid receptor can both promote and inhibit prostate cancer progression, depending on the ...

A recent study from the Institute of Biomedicine at the University of Eastern Finland shows that the glucocorticoid receptor can both promote and inhibit prostate cancer progression, depending on the ...

Glucocorticoid receptors (GRs) are ligand-activated transcription factors that play a pivotal role in mediating the effects of endogenous and synthetic glucocorticoids. These receptors regulate a ...

New research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance ...

Recent research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance ...

The REPLENISH trial finds secukinumab doubles the remission rate and significantly lowers steroid use in relapsing ...

A team from the UB has described for the first time the molecular self-assembly process of this key protein and has revealed how its active conformation differs from the traditional model accepted for ...

The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I ...

Abbvie Inc. recently disclosed the discovery and structure of the anti-tumor necrosis factor (TNF) glucocorticoid receptor modulator (GRM) immunology antibody-drug conjugate (iADC) ABBV-154. The drug ...

Childhood abuse, one of the most commonly reported traumatic exposures in the United States, does not merely leave psychological scars. A growing body of postmortem brain studies and clinical ...