A new study led by Western researchers is the first to identify a factor that could influence how fast the pocket where human ...

HIV-1 particles are released from infected cells in an immature, non-infectious form. The main building material for a virus particle is about 2,000 copies of a long, rod-shaped protein called Gag.

They graphically represent the life cycle of HIV-1, from the initial binding of the viral particle onto a host cell (Viral Entry), through insinuation into the host cell's nucleus to spark the ...

It was previously demonstrated that the HIV-1 integrase (IN)-interacting host factor INI1/SMARCB1 binds to HIV-1 IN through its Rpt1 domain of INI1 (INI1-Rpt1) and plays a key role in assembly and ...

Protein crystallization at the SER-CAT beamline at Argonne’s Advanced Photon Source proved key to the discovery of a new HIV vaccine candidate.

In the Virus-Like Particle Translational Oncology Laboratory, Qizhi Cathy Yao, M.D., Ph.D. is developing non-infectious HIV virus-like particles (VLPs) as candidate HIV mucosal vaccines for both ...

To become infectious, HIV has to undergo a maturation process, which involves a rearrangement of the matrix proteins (red). In an immature virus particle, the matrix proteins form a lose lattice ...