While most approved antibody therapies – like Daiichi Sankyo and AstraZeneca’s Enhertu (trastuzumab deruxtecan) – are based on the immunoglobulin G (IgG) isotope ... functions into a single antibody ...

The properties of the different IgG isotypes should ... for the original or a different half-molecule and is driven by the relative amounts of both parent antibodies. An excess of either antibody ...

Research has shed light on how a new type of antibody treatment reactivates patients' immune cells to fight ovarian cancer.

Now, Epsilogen's portfolio can span antibodies which combine IgE and IgG functionality into a single molecule (IgEGs), bispecific IgEs and IgEGs that can bind two different antigens simultaneously ...

The drug delivery system, which he calls in vivo antibody painting, is itself a peptide and is composed of a binder region that attaches to the IgG, a payload region that carries the GLP-1 ...

Looking ahead, Epsilogen sees the deal as giving it the option to “mix and match IgE, IgA and IgG functionality into a single antibody molecule.” “Such hybrid antibodies have the potential ...

Recent transfusion of immunoglobulin-containing products. The presence of antibodies without viral antigen or DNA. The presence of IgG anti-HBcAb but lack of IgM anti-HBcAb antibody (in our case ...