A research team led by Professor Ki-Young Lee at the College of Medicine, Sungkyunkwan University, has uncovered a previously unrecognized tumor-intrinsic role of the immune checkpoint molecule PD-L1, ...

Intracellular peptides, generated predominantly via the ubiquitin–proteasome system, have emerged as critical modulators of cell signalling. These peptides play multifaceted roles, ranging from ...

Immunotherapy has transformed the way physicians treat patients. In the context of cancer, immune cells are suppressed and become inert as a result of tumo | Immunology ...

Background: Wnt signaling affects fundamental development pathways by regulating cell proliferation and differentiation. Aberrant activation of Wnt/ß-catenin signaling promotes the development of ...

A precision-engineered decapeptide reshaping how researchers approach melanogenesis modulation at the enzymatic level.

Enveric Biosciences (ENVB) announced new mechanistic data demonstrating that its lead candidate, EB-003, activates both Gq- and ss-arrestin-mediated signaling downstream of the 5-HT2A receptor.

The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching effects regarding immune responses, inflammatory processes, and diseases. A ...

Designated areas (white circles) were irradiated with blue light at specific frequencies (indicated in the top left of each panel) to examine chemotactic aggregation. A research team led by Dr.

Enveric Biosciences ENVB on Thursday shared new mechanistic data demonstrating that its lead candidate, EB-003, activates both Gq- and β-arrestin–mediated signaling downstream of the 5-HT₂A receptor.

Proprietary assays demonstrate dual Gq and β-arrestin signaling at 5-HT₂A, pathways linked in peer-reviewed studies to ...