Novel nephron organoids that can be fine-tuned to represent the proximal convoluted tubule or loop of Henle have been ...

The incidence of premature delivery has increased substantially in the past decade, such that 6–10% of all births in the Western world are premature (1). Moreover, as a result of marked advances in ...

In this paper, concepts from network automata are adapted and extended to model complex biological systems. Specifically, systems of nephrons, the operational units of the kidney, are modelled and the ...

Scientists identify a possible therapeutic target to extend kidney development in preterm babies that would reduce the risk of kidney failure later in life. Study identifies possible therapeutic ...

The Clinical Implications of Basic Research series has focused on highlighting laboratory research that could lead to advances in clinical therapeutics. However, the path between the laboratory and ...

A new consortium to accelerate the discovery of novel drugs to treat kidney diseases was announced Monday 6 November. The NEPLEX (nephron on a chip with cellular and extracellular matrix complexity) ...

A growing repertoire of cell and molecule-based immunotherapies is offering patients with indomitable cancers new hope by mobilizing their immune systems against tumor cells. An emerging class of such ...