Cutaneous leishmaniasis exhibits a wide spectrum of clinical presentations that is determined largely by the host immune response. The host immune response to infection is influenced both by host ...

Visceral leishmaniasis (VL) is a systemic protozoan disease that is transmitted by phlebotomine sandflies. Poor and neglected populations in East Africa and the Indian sub-continent are particularly ...

Leishmaniasis is a tropical disease caused by a parasite called Leishmania donovanii. Sand flies of the Phlebotomus family spread these parasites through their bites. The different forms of human ...

In recent years, physicians and scientists in parts of Brazil where visceral leishmaniasis (VL) is endemic have seen rising numbers of cases of co-infection by Leishmania infantum and Crithidia, also ...

Leishmaniasis is a parasitic disease that affects up to 1 million people worldwide each year. It is caused by the protozoan Leishmania, transmitted through the bite of a sandfly. Once inside its ...

In diffuse cutaneous leishmanisis (DCL), a rare form of leishmaniasis, parasites grow uncontrolled in skin lesions across the body. For the first time, researchers reporting in PLOS Neglected Tropical ...

An otherwise healthy 42-year-old man presented with a small erythematous nodule on the superior part of his right ear and substantial swelling of the entire pinna (Figure 1A), which he had first ...

Small, inconspicuous skin lesions may heal by themselves, even without treatment. This can take months or even years. Ugly scars are often left behind. If the sores are large or located in ...

Researchers have taken an important step forward in developing a controlled human infection model to test leishmaniasis vaccines. Researchers have taken an important step forward in developing a ...

Humans can tolerate the parasites responsible for the sleeping sickness, Chagas disease and leishmaniasis for many years. These parasites belong to the same family of pathogens known as ...

Researchers say they have developed a novel, safe, and effective way to infect volunteers with the parasite that causes leishmaniasis and measure the body’s immune response, bringing a vaccine for the ...