Background: Monoclonal free light chains (FLCs) frequently cause rapidly progressive renal failure in patients with multiple myeloma. Immunoassays which provide quantitative measurement of FLCs in ...

Therapy-related B-lymphoblastic leukemia (B-ALL) following treatment for multiple myeloma is ... of B-ALL with surface kappa light chain expression post-myeloma treatment was made.

Kidney dysfunction: In multiple myeloma, proteins known as free light chains build up in the kidneys, causing impaired function or "renal insufficiency." Signs include changes in urine frequency ...

Multiple myeloma is a type of blood cancer caused by a buildup of abnormal plasma cells in the bone marrow. As the abnormal ...

"The evolution of the definition for high-risk multiple myeloma will help identify patients with light chain cast nephropathy, which is a key myeloma defining event for symptomatic multiple ...

A multiple myeloma diagnosis is a life event that can be overwhelming. Get trusted information for every step of your journey. Multiple myeloma can be tricky. That’s because it sometimes has no ...

Therapy-related B-lymphoblastic leukemia (B-ALL) following treatment for multiple myeloma is a rare occurrence. Despite its rarity and the lack of ...

So what you want to determine is, how serious is the multiple myeloma? How extensive is it? How is it affecting other organs? There's a big spectrum with multiple myeloma and all these plasma cell ...

Multiple myeloma is when the plasma cells grow out of control and become cancerous. It can sometimes be mistaken for other plasma cell disorders like: This staging classifies myeloma in three ...

A stem cell transplant can be a good treatment for multiple myeloma. A successful transplant gives someone with multiple myeloma new, healthy bone marrow. It replaces the bone marrow harmed by myeloma ...

Before serum FLC assays became available, urine analysis was the preferred method for identifying monoclonal FLC production in routine haematological screens for multiple myeloma and other ...