Antibody molecules ... are found to have a fundamentally similar structure consisting of two heavy and two light peptide chains. Recent studies of the amino-acid sequences of these chains are ...

The method for creating bispecific κλ bodies is simple: a production cell expresses a single heavy chain, alongside κ and λ light chains, which self-assemble into functional antibodies.

Lonza’s bYlok® technology is changing the way bispecific antibodies are designed. Achieving the correct heterodimerization of light and heavy chains during bispecific production can be challenging, ...

Single-Chain Variable Fragments (scFvs): They are the smallest functional antibody fragments and include variable regions of light and heavy chains connected through a flexible linker. These are ...

The heavy and light chains of that fully human anti-human eosinophil mAb were delivered via an adeno-associated virus (AAV)-based gene therapy to immunodeficient mice, where they suppressed levels ...

Partnership leverages AbTherx's Atlas Binary Fixed Light Chain Mouse to accelerate Rondo's pipeline of bispecific antibodies MOUNTAIN VIEW, CA / ACCESS Newswire / April 23, 2025 / AbTherx, Inc., a bio ...