Single-Chain Variable Fragments (scFvs): They are the smallest functional antibody fragments and include variable regions of light and heavy chains connected through a flexible linker. These are ...

The method for creating bispecific κλ bodies is simple: a production cell expresses a single heavy chain, alongside κ and λ light chains, which self-assemble into functional antibodies.

Antibody molecules ... are found to have a fundamentally similar structure consisting of two heavy and two light peptide chains. Recent studies of the amino-acid sequences of these chains are ...

Lonza’s bYlok® technology is changing the way bispecific antibodies are designed. Achieving the correct heterodimerization of light and heavy chains during bispecific production can be challenging, ...

The heavy and light chains of that fully human anti-human eosinophil mAb were delivered via an adeno-associated virus (AAV)-based gene therapy to immunodeficient mice, where they suppressed levels ...

Partnership leverages AbTherx's Atlas Binary Fixed Light Chain Mouse to accelerate Rondo's pipeline of bispecific antibodies MOUNTAIN VIEW, CA / ACCESS Newswire / April 23, 2025 / AbTherx, Inc., a bio ...

Nona Biosciences, a global biotechnology company providing integrated solutions from "Idea to IND" (I to ITM), ranging from ...