This is a major source of cardiovascular morbidity and mortality. We have never been able to treat lipoprotein(a) until now.” ...

Low-density lipoprotein (LDL) cholesterol, or “bad” cholesterol, collects in the walls of the blood vessels, causing them to narrow. High-density lipoprotein (HDL), or “good” cholesterol ...

To solve this dilemma, the body transports fat and cholesterol by coating them with a water-soluble "bubble" of protein. This protein-fat bubble is called a lipoprotein. Total cholesterol should ...

When cholesterol and proteins combine, they’re called lipoproteins.” Low-density lipoprotein (LDL) and high-density lipoprotein (HDL) are the two main types. “LDL is unhealthy and can cause ...

Heart disease experts are hailing the results of a clinical trial showed a strongly positive performance by a drug that ...

The core of the lipoprotein, containing cholesterol ester and TG, is nonpolar and hydrophobic, and the outer layer of the lipoprotein particle (containing free cholesterol, phospholipid ...

Eli Lilly on Sunday said the Phase 2 study of lepodisiran, designed to lower the production of lipoprotein (a), or lp (a), met its primary endpoint, reducing lp (a) levels by an average of 93.9% over ...

People with low levels of low-density lipoprotein cholesterol (LDL-C) in their blood have a lower risk of dementia, including lower risk of Alzheimer's disease-related dementia, shows a study ...

Elevated lipoprotein(a) concentrations are associated with atherosclerotic cardiovascular disease. The safety and efficacy of lepodisiran, an extended-duration, small interfering RNA targeting ...

The research, published in the journal of Neurology Neurosurgery and Psychiatry, found people with low levels of low-density lipoprotein cholesterol (LDL-C) in their blood have a lower overall risk of ...

AZD0780 demonstrated a statistically significant low-density lipoprotein cholesterol reduction when administered on top of standard-of-care statin therapy, as compared with placebo. AZD0780 is an ...

Body weight also affects cholesterol levels. “Obese or overweight individuals are at a higher risk of producing LDL ...