Emerging insights into type 2 inflammation are reshaping understanding of CSU and expanding opportunities for targeted ...

The bone marrow immune microenvironment plays a poorly understood role in renal anemia. This study aimed to investigate the independent and combined effects of mast cell activation (basal serum ...

Allergic reactions after COVID shots appear only in participants with severe allergy and/or mast cell disorder histories, but ...

The interaction between mast cells and other immune cells at sites of allergic responses has been largely unexplored. A research group at the MPI of Immunobiology and Epigenetics used specialized ...

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy ...

Innate immune cells are white blood cells that mediate innate immunity and include basophils, dendritic cells, eosinophils, Langerhans cells, mast cells, monocytes and macrophages, neutrophils and NK ...

The itching, redness and swelling of an allergic reaction are caused by mast cells—the vigilant first responders of the immune system that spring into action with histamine-filled granules in response ...

Please provide your email address to receive an email when new articles are posted on . Barzolvolimab is an anti-KIT monoclonal antibody, and mast cells need KIT to survive. Weekly hive and itch ...

Sneezing, runny nose, itchy skin. When the body reacts to pollen or dust mites, it is the mast cells lurking in the skin and ...

Mast cell tumors (MCTs) are among the most common skin cancers affecting dogs and cats. These tumors originate from mast cells – immune cells that play a key role in allergic reactions and ...

Serum-based mast cell testing correlated with airway responses to cat allergen in a small study, but further diagnostic validation is needed.