The deal gives the Anglo-Swedish drugmaker complete control of Caelum's late-stage medicine for light chain (AL) amyloidosis, a potentially fatal disease that causes the rogue protein amyloid to ...

Joint pain occurred more often in people who received treatment for light-chain amyloidosis. Keep in mind that Darzalex Faspro was prescribed with other medications to treat multiple myeloma in ...

In addition, Light Chain has developed candidates for indications beyond oncology, including NI-2101 for Takeda, which targets factor IX and factor X for the treatment of hemophilia.

The following is a summary of “Diagnostic Utility of Kappa Free Light Chain Index in Adults With Inaugural Optic Neuritis,” ...

Paradox is focused on the development of treatment for immunoglobulin light chain amyloidosis (AL amyloidosis), a complication of multiple myeloma that can lead to heart, kidney and liver failure ...

Background: Monoclonal free light chains (FLCs) frequently cause rapidly ... patients will allow early initiation of disease specific treatment, such as chemotherapy plus or minus therapies ...

Neurofilament light chain and glial fibrillary acidic protein level increases were associated with cognitive decline in T2D with obesity.

The study compared three types of blood biomarkers: neurofilament light chain proteins, glial acidic proteins and phosphorylated tau 181. Neurofilament light chain proteins can be detected in the ...