Researchers used consumer-grade 3D printers to create sub-$1 optical lenses that enable super-resolution nanoscale biological ...

Example of super-resolution microscopy: The image shows how the Discrete Molecular Imaging (DMI) technology visualizes densely packed individual targets that are just 5 nanometer apart from each other ...

What is Structured Illumination Microscopy? Structured Illumination Microscopy (SIM) is a super-resolution fluorescence microscopy technique that allows for imaging beyond the diffraction limit of ...

Deblurring by pixel reassignment remaps raw fluorescent microscopy images to sharpen images via pixel reassignment. Credit: Zhao and Mertz, doi 10.1117/1.AP.5.6.066004. Obtaining high-resolution ...

Researchers have shown that consumer-grade 3D printers and low-cost materials can be used to produce multi-element optical ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

Microscopes have long been scientists’ eyes into the unseen, revealing everything from bustling cells to viruses and nanoscale structures. However, even the most powerful optical microscopes have been ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

Zeiss Microscopy, Jena, Germany, a manufacturer of visible, electron, X-ray and ion microscope systems, has added two super-resolution microscopes to its structured illumination microscopy (SIM) range ...