Elsewhere in the show, Dave Chappelle introduced a performance by Lil Wayne, who was also backed by The Roots. He performed a medley of hits featuring “Uproar,” “Lollipop,” “6 Foot 7 Foot,” “Mrs. Officer,” and “A Milli.”

Miley Cyrus and Brittany Howard covered Queen’s “Crazy Little Thing Called Love” at SNL50: The Homecoming Concert, which aired on Peacock. Tonight the pair returned for the big SNL 50: The Anniversary Celebration on NBC primetime.

Miley Cyrus, Brittany Howard, and the Roots paid tribute to Sinead O'Connor with a performance of 'Nothing Compares 2 U' on 'SNL50.'