1. Theoretical models suggest that increased vector species participation in pathogen transmission significantly increases the prevalence of vector and host infections. However, there has been a lack ...

While gene therapy of simple Mendelian disorders often requires the substitution of only a single therapeutic gene, the treatment of complex disorders and infectious diseases may necessitate the ...

In mammalian cells, the dox-regulated system is mainly used for the induction of a target gene under transcriptional control of a Tc-responsive element (TRE) promoter that contains tetO-binding sites ...

In recent years, we have seen rapid growth in the development of adeno-associated virus (AAV)-mediated gene therapy products that target fatal and highly debilitating diseases. Growth is evident in ...