The first article in Cell, "Development of Clinically Viable Non-Muscle Myosin II Small Molecule Inhibitors," details the optimization and development of a new pharmacological cla ...

Myosin is also responsible for muscle contractions like your heartbeat that happens at regular intervals. Understanding Muscle Contractions ‌ Concentric Contractions .

Experimental myosin inhibitor MT-125 sensitizes glioblastoma to radiation and kinase inhibitors, prolonging survival in mouse models.

A potential treatment for glioblastoma crafted by scientists at The Wertheim UF Scripps Institute renders the deadly brain ...

Methods: Blood samples were obtained from 51 non-sports people and 38 sportsmen with skeletal muscle injury. Western blood analysis was performed to determine fast and slow myosin and creatine kinase ...

Myosin and actin filaments interact with each other to initiate muscle contractions and, over time, mechanical stress caused by constant movement will damage these protein filaments.

Title: EDG-5506 Targets Fast Skeletal Myosin to Protect Dystrophic Muscle and Reduce Muscle Damage Biomarkers in a Phase 1 Trial in Becker Muscular Dystrophy (BMD) (P.124) Date: Friday, October 14 ...

Edgewise Therapeutics’ lead candidate has been shown to reduce levels of a biomarker related to skeletal muscle damage in a phase 2 trial.. The biotech had been testing sevasemten, an orally ...

Cardiac muscle tissue exists only in the heart. Here, it is responsible for keeping the heart pumping and relaxing normally. Conditions that affect this tissue can affect the heart’s ability to ...