The unique feature of the myosin-V S1, the long lever arm, should, according to the swinging cross-bridge model, allow for a much longer step size than that observed for myosin II.

"Myosin walks like we walk, but with a 74-nanometer stride that is more than 10 million times smaller than ours," said Paul Selvin, a professor of physics at the University of Illinois at Urbana ...

The research, which has direct implications for how root systems manage responses to plant hormones, also has broader implications for understanding the condensation of other motile proteins that move ...

Muscle myosin, whose study dates back to 1864, has served as a model system for understanding motility for decades. Kinesin, discovered ...

While the study focused on A. thaliana, a model plant, ... Loss of myosin XI disrupts AtNIP5;1 positioning, impairs endocytic trafficking, and reduces boron absorption, ...

Myosin-5 working stroke and walking on F-actin. (Credit: Klebl et al., 2024) The past years has seen many refinements in cryo-EM, with previously quite manual approaches shifting to microfluidics ...

In a recent study published in Nature Communication, researchers employed artificial intelligence (AI)-driven virtual screening to discover 'F10', a novel cardiac-specific myosin inhibitor for ...