Figure 1: The adult zebrafish kidney undergoes nephrogenesis throughout life and after injury. Figure 2: The adult zebrafish kidney contains transplantable progenitors that form functional nephrons.

Following kidney injury, repair can result in functional tissue becoming a patch of cells and disorganized extracellular matrix—a scar—or it can recapitulate the original tissue architecture through ...

Perfectly punctual or fashionably late, it takes all kinds to build a kidney. So it is for stem cells building kidney tissue discovered timing is critical as the precise arrival of progenitor cells ...

The Clinical Implications of Basic Research series has focused on highlighting laboratory research that could lead to advances in clinical therapeutics. However, the path between the laboratory and ...

A pair of USC Stem Cell mouse studies detail how progenitor cells self-renew, differentiate, and aggregate into early kidney structures, offering insights for the creation of stem cell-based ...

Glomeruli are at the heart of renal function, and yet are only part of an intact nephron. They are of irreplaceable value in maintaining homeostasis. The intact nephron theory: Each nephron is a ...

Arriving early or late can have big consequences for early-stage cells that gather to form a new kidney, USC researchers discovered. The scientists showed how progenitor cells that form the kidney’s ...