Cancer treatment is the arena in which information from the human genome project is being translated most readily into personalized treatment 1. Malignant progression is driven by molecular ...

The compound, known as PI-103, shows unique potency against cancer cell proliferation in studies of mice with grafts of human glioma cells. Gliomas are the most common form of brain cancer, and have ...

PI3 kinases are obvious targets for researchers developing cancer drugs. Formally known as phosphatidylinositol-3 kinases, the enzymes are involved in a laundry list of functions that contribute to ...

Closely related enzymes often serve different cellular functions, but sorting out their distinct roles and the selectivity of their interactions with druglike compounds remains challenging. A new ...

According to the researchers at the University of California, San Francisco (UCSF) they have identified a class of compounds that prevents the growth of brain cancer According to the researchers at ...