LEARNING POINTS Raised serum globulin concentration or total protein may be the first indication of a paraprotein, but a raised globulin level is more commonly due to polyclonally raised globulins in ...

The PRONTO amyloidosis study: A randomized, double-blind, placebo-controlled, global, phase 2b study of NEOD001 in previously treated subjects with light chain amyloidosis and persistent cardiac ...

The stage of your myeloma tells your doctor about how it is affecting you and how it might develop. Doctors use the international staging system to stage myeloma. There are 3 stages: stage 1, stage 2 ...

Here, we compare the use of IgGκ/IgGλ and IgAκ/IgAλ HLC assays with conventional measurements for quantification of M-Igs and for response assessment, and evaluate the advantages and limitations of ...

In this article, the IMWG’s guidelines for approaching relapsed multiple myeloma (MM) are discussed. Overall the article nicely summarizes the basic principles of IMWG’s recommendations. The ...

A phase II study of Epothilone B analog BMS-247550 (NSC 710428) in patients with relapsed aggressive non-Hodgkin’s lymphomas No significant financial relationships to disclose. This is an ASCO Meeting ...

Waldenström macroglobulinemia, a condition that most commonly occurs in lymphoplasmacytic lymphoma, typically manifests with diffuse lymphadenopathies, cytopenias, and a markedly elevated erythrocyte ...

Waldenström's macroglobulinemia is a lymphoproliferative disorder characterized by a lymphoplasmacytic bone marrow infiltrate and high levels of a monoclonal IgM in serum. 1 A number of ...