Knowledge about an antibody’s epitope binding site is beneficial to researchers for many reasons, as recently described in a blog post by Callahan. For example, post-translational modifications ...

Proteins may have multiple names, isoforms, splice variants, and post-translational modifications. If your research depends on the antibody recognizing a specific portion of your target, note the ...

“Progressing antibodies to the clinic is challenging ... contain important post-translational modifications required for function, and be directly translatable to the final manufactured product ...

Monoclonal antibodies are considered the most rapidly growing ... strategies for deciphering the structure of proteoforms and the presence of post-translational modifications. In this webinar, our ...

with post-translational modifications, and carrying disease mutations. However, Burmer estimates that the number of highly validated antibodies (such as those used in diagnostics) is to fewer than ...

This useful study reports a method to detect and analyze a novel post-translational modification, lysine acetoacetylation (Kacac), finding it regulates protein metabolism pathways. The study unveils ...

and post-translational modification detection from body fluids, cultured cells, and tissues. While highly efficient and robust, affinity proteomics is limited to well- characterized proteins with ...

Top-down proteomics: Intact proteins are ionized and analyzed directly, allowing for the study of proteoforms and ...

Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein. Gene regulation gives the ...