Researchers reprogrammed bacterial bridge recombinases to edit large genomic regions in mammalian cells, revealing a ...

CRISPR-Cas9 has transformed our ability to study DNA by manipulating genomic information in a programmable fashion. The RNA-targeting CRISPR effector protein Cas13 is poised to revolutionize the study ...

In recent years, the scientific community has made significant strides in the field of gene editing, particularly through the development of the CRISPR (Clustered Regularly Interspaced Short ...

Allison DeAngelis is the East Coast biotech and venture capital reporter at STAT, reporting where scientific ideas and money meet. She is also co-host of the weekly biotech podcast, The Readout Loud.

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects. Utilizing this system, ...

In a recent study, researchers manipulated cellular proteins that control genes in aged mice. Experimental results showed their livers were rejuvenated to younger states. This work shows promise as a ...

With a shared purpose, we can realize the true promise of CRISPR and improve healthcare, providing hope to more patients with ...

When a neuron in our body gets damaged, segments of RNA produce proteins that can help repair the injury. But in neurological disorders such as ALS and spinal muscular atrophy, or following spinal ...

A landmark Huntington's trial slows disease progression by 75%, signalling how RNA- and CRISPR-based tools redefine treatment for rare genetic disorders. Significant advancements in gene silencing and ...