Schwann cells are derived from the neural crest and play crucial roles in the maintenance and regeneration of the motor and sensory neurons of the peripheral nervous system (PNS).

When Schwann cell function returned, so did the mice’s ability to detect vibrations. The team was further able to identify differences in sensory input from Schwann cells using optogenetics, ...

Corneal nonmyelinating Schwann cells illuminated by single‐cell transcriptomics and visualized by protein biomarkers. Journal of Neuroscience Research , 2020; DOI: 10.1002/jnr.24757 Cite This Page : ...

Myelin-making Schwann cells have an ability every aging Hollywood star would envy: they can become young again. According to a study appearing in the May 19 issue of the Journal of Cell Biology ...

The researchers discovered that Schwann cells “sense” when axons become sick, and in response provide them with increasing amounts of sugar products as an energy source to promote axon stability. At ...

Researchers reveal how cells in the peripheral nervous system degrade myelin after nerve injury, a process that fails to occur in the central nervous system. The results could provide new targets ...

The authors show that nerve injury induces expression of NRG1 type I in Schwann cells and that this expression is necessary for efficient remyelination. In addition, axonally expressed NRG1 type ...

Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves. The Journal of Cell Biology , 2015; 210 (1): 153 DOI: 10.1083/jcb.201503019 Cite This Page : ...

Schwann cells are cells defined by their intimate relationship with axons in the peripheral nervous system throughout development. 1 Schwann cell precursors depict the earliest developmental stage ...

World's first trial to test safety of cell regeneration for paralyzed patients. July 31, 2012— -- Marc Buoniconti has been paralyzed from the neck down for 27 years after a college football ...

New research reveals for the first time that despite the fragility of axons, Schwann cells — which surround axons within nerves like a glove covers a hand — can come to the assistance of injured axons ...

Neuroscience researchers at UConn Health are finding genetic properties of Schwann cells in the cornea that may unlock a better understanding of their role in healing, sensory function, preserving ...