Physician-scientist Richard J. Wong’s laboratory is investigating ways to change the cancer ecosystem to make it less hospitable. Cancer relies on many tricks to survive and grow. One tactic is to ...

Scientists show that Schwann cells take over functions of immune cells in nerve healing. Similar mechanisms could prevent nerve tumors from growing. Schwann cells are known to protect and repair nerve ...

The Feltri lab seeked to understand how cell-cell and cell-extracellular matrix interactions contribute to cell shape and polarity within a developing tissue. They applied these biological questions ...

Researchers in Germany report a major finding in the field of neuroscience that could have important ramifications in new pain therapies targeting Schwann cells in the skin. Classical understanding of ...

Following an injury, such as a traumatic crush injury, the peripheral nervous system is itself often able to effectively regenerate. This regeneration capacity is mainly attributable to the Schwann ...

Damage to the body's peripheral nerves can cause pain and movement disorders. Researchers have recently investigated how damaged nerves can regenerate better. They found that fat tissue strongly ...

Endogenous pyruvate is an end-product in glycolysis and a key molecule for ATP production under aerobic and anaerobic conditions, whereas exogenous pyruvate is transferred to cells via monocarboxylate ...

A new approach to repairing peripheral nerves marries the regenerating power of gingiva-derived mesenchymal stem cells with a biological scaffold to enable the functional recovery of nerves following ...