Before serum FLC assays became available ... However, the collection of urine samples, particularly 24 hour collections, is frequently problematic. In one screening study, urine samples were ...

is determined by demonstration of a monoclonal immunoglobulin molecule or chain in serum and/or urine. Previous results on immunofixation electrophoresis (IFE) and quantitative free light chain ...

Serum free light chain testing is a boon to detecting multiple myeloma without requiring a 24 hour urine sample, however the user needs to be aware of the high-dose hook effect which can produce ...