Genetic disorders involving the skeletal system arise through disturbances in the complex processes of skeletal development. The new online resource gives detailed information about more than 80 of ...

Thanks to major progress in the understanding and management of rare congenital diseases and syndromes, many patients with these rare disorders are now living longer lives. With this progress it has ...

Gain-of-function mutations in fibroblast growth factor receptor (FGFR) genes are known to cause a range of skeletal disorders, such as craniosynostosis and chondrodysplasia, which severely affect ...

As part of our natural bone development, special cells on the surface break down old bone tissue and then build it back up again. When changes occur to this cycle and throw things off balance, ...

Elvire Gouze Ph.D., a serial entrepreneur and expert in skeletal disorders, has formed another company—InnoSkel—after agreeing to sell her first venture Therachon to Pfizer for $340 million upfront ...

This illustration shows the major cell types affected by cellular senescence in various skeletal diseases. As the body ages, senescent cells accumulate in different tissues—including bone, cartilage, ...

Researchers at the Garvan Institute of Medical Research have discovered a new type of bone cell that may yield novel therapeutic targets and strategies for osteoporosis and other skeletal diseases.