The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...

Between the axon of a transmitting neuron and the dendrite of a receiving neuron is a gap called the synapse—the site at which signals are passed between the brain cells. The nervous system ...

Furthermore, we currently have little understanding of the functional states of synapses on a cell-assembly basis. What is the overall signaling impact of synaptic inputs at physically non ...

Early menopause and poor brain-connection health may interact to increase Alzheimer's disease risk in women, a study found.

This webinar will highlight how the evaluation of IS formation at the single-cell level can support the discovery of new ...

An electrical impulse cannot directly cross the gap so a different mechanism has to be used. Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent ...

Thanks to Olson, Manor and his team obtained cochlear samples from adult mice that had normal hearing and were either exposed ...

T cells, move over. B cells are now reported, in a recent paper in Nature, to have their own immunological synapses with APCs. Only this time the antigen is whole and B cells don't keep it to ...

Although chimeric antigen receptor T-cell therapy has raised hopes for long-term remission in autoimmune disease, it has ...

Erythropoietin-producing hepatoma (Eph) receptors, including EphA4, are expressed on the cell surface and involved in brain development, which involves extensive pruning of synapses. A variant in ...

With these synchronized neuron cultures, the team observed their gradual maturity over 100 days by monitoring the development of synapses, cell length, and electrical properties. By using RNA ...