The third type of neurotransmitter - neuromodulators - work differently; they are not confined to the synaptic cleft between just two nerve cells but can regulate many neurons simultaneously.

These cross the synaptic cleft and dock to specific "antennae" on the postsynaptic side. This causes them to also trigger electrical pulses in the receiver cell.

Single-molecule imaging has revealed that synapses – the tiny junctions that allow neurons to communicate with each other – transmit information across precisely-aligned nanocolumns. The ...

There is accumulating evidence that glial cells actively modulate neuronal synaptic transmission. We identified a glia-derived soluble acetylcholine-binding protein (AChBP), which is a naturally ...

Studies have shown that hippocampal learning tasks lead to an increase in levels of cell adhesion molecules in the synaptic cleft. This highlights their role in synaptic plasticity, demonstrating ...

When the neurotransmitter binds to the neuron on the other side of the synaptic cleft, that post-synaptic neuron may change in some way. Neuroscientists are continuing to discover just how brain ...

When a presynaptic cell is electrically excited, synaptic vesicles fuse with the presynaptic membrane causing messenger substances within the vesicles to be released into the synaptic cleft.

(1) A nerve impulse arrives. (2) This causes calcium ion channels to open, resulting in an influx of calcium ions in the terminal. (3) This causes synaptic vesicles to fuse with the terminal ...

Since an SSRI blocks the normal reuptake of serotonin from the synaptic cleft, the neurotransmitter stays in this extracellular space longer than normal, and in response, the brain’s synthesis ...

These cross the synaptic cleft and dock to specific "antennae" on the postsynaptic side. This causes them to also trigger electrical pulses in the receiver cell. "However, ...