Harvard researchers have mapped and catalogued more than 70,000 synaptic connections from about 2,000 rat neurons, using a ...

Neuron Function Synapses Neural synapses are junctions ... to action potentials and voltage-gated calcium channels. Once they traverse the gap between neurons (synaptic cleft), neurotransmitters ...

Researchers have identified the mitochondrial calcium uniporter as a critical protein in the strengthening of synaptic ...

Pyramidal-neuron dendrites contain voltage-gated channels that can influence synaptic integration. These channels can also support backpropagating action potentials and dendritically initiated spikes.

Scientists have uncovered a crucial pathway that links brain cell activity to the activation of genes responsible for ...

To make their model more realistic, they measured SIE in the presence of a high level of background synaptic activity, and used increasingly complex models of the postsynaptic neuron. Finally ...

An electrical impulse cannot directly cross the gap so a different mechanism has to be used. Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent ...

A team of researchers from the University of Massachusetts Amherst is the first to show how proteins called "chaperones" are vital in ensuring that neurons can transmit signals to one another.

Sleep's role to down-scale glutamate, excitatory, frontal cortical synapses is extended to include an up-scaling of metaplastic LTP potential, in recovery from prolonged waking induced saturation of ...

“iAssembloids are a scalable platform bridging the gap between 2D cultures and ... ApoE4 versus ApoE3 astrocytes modulated neuron survival. ApoE4 astrocytes boosted neuronal expression of genes ...

The entorhinal cortex (EC) plays a pivotal role in memory function and spatial navigation, connecting the hippocampus with the neocortex. The EC integrates a wide range of cortical and subcortical ...