Systemic amyloidoses are potentially lethal ... Chemotherapy in immunoglobulin light chain amyloidosis (AL). - Liver transplantation in ATTR amyloidosis. - Elimination of underlying inflammation ...

But in this disease, light chains misfold and aggregate into amyloid fibrils that deposit in organs and tissues. In a review ...

but they are also present in a number of systemic amyloidosis conditions including light chain amyloidosis and transthyretin amyloidosis. Amyl Therapeutics, headquartered in Liège, Belgium ...

DNA analysis of TTR gene to detect or exclude hereditary transthyretin-related amyloidosis (ATTR). - Serum free light chain assay to detect low grade plasma-cell dyscrasia. - Mass spectrometry for ...