One type of higher-order assembly is the hexagonal bundle found within filopodia. A protein called fascin binds and bridges pairs of actin filaments, stitching them into bundles. These bundles are ...

Filopodia are specialized structures that extend from the cell membrane to allow a cell to explore the environment around it. These thin protrusions are full of a protein called actin, which, in ...

Oxidative stress induces filopodia formation and secretion of CD9/CD44(+) filopodia-derived sEVs in Hela cells. Hela cells were treated with or without H2O2 for 6 h to induce oxidative stress and ...